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Assume the sales mix remains the same at all levels of sales except for requirement i
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Both compounds show measurable weight loss within the first 4-8 weeks of treatment, though most of this initial period involves dose titration rather than maximum efficacy
The topical route is the format with the strongest human clinical trial evidence for skin outcomes, from the landmark 1998 Abdulghani study that outperformed both vitamin C and tretinoin to the Finkley skin-thickness data
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